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PHARMADRY® 真空卧式桨叶干燥机

信息来源: | 发布日期: 2012-12-21 | 浏览量:
关键词:PHARMADRY干燥机,PHARMADRY真空卧式桨叶干燥机,PHARMADRY®真空桨叶干燥机

PHARMADRY® 真空卧式桨叶干燥机

主要是原料药和精细化工产品的干燥的PHARMADRY®卧式真空桨叶干燥机。 除了其较低的资本投资成本,本机的主要优点是其短的周期时间,防止异物污染,操作简单,容易验证,以及促进清洁和检查。 的干衣机,特别适合于使用在洁净室和无菌应用。该机器设计和建造的每cGMP和FDA的指导方针。

的PHARMADRY®的重要特点是: •平焊回平盖和铰链前门开在整个血管直径的圆柱型,卧式容器。当门打开时,机器内部的清洗和检查的目的完全访问。 •与产品如容器接触的所有表面,后盖,前门,搅拌器和蒸汽过滤器被加热时,提供了非常有效的热交换。 •的圆筒形容器中,后盖,前门和搅拌器的加工,以保证最小的可能的搅拌器和血管壁之间的公差。 •最小公差也可以很好的热交换,防止产品合规性。 •所有内表面镜面抛光处理,以提高流动行为的预防口服amiodarone粉状产品,以及以方便清洁。 •搅拌器被安装在干衣机的背面,该船只的一侧上支持  - 搅拌器设计以满足要求的这个特定干燥器类型,以保证良好的混合均匀的行动整个干燥器体积,也反向操作,以提供良好的放电特性,并在相同的时间,减少摩擦至最小,以在产品上防止局部过热,以及防止推力或本地产品压缩。  - 加快电动驱动或液压传动与控制阀的可调使用频率转换器,  - 搅拌轴密封采用双端面机械密封或填料函。

•机械密封机械密封 安装在后盖,非常便于清洁和维护的目的。干或湿的正在运行的机械密封可以安装。

•机械密封的优点:  - 更好的最终真空  - 没有危险的泄漏或排放  - 没有产品污染  - 无菌操作的可能性  - 故障检测系统的机械    密封

•有多个唇式密封填料箱要求不高的应用程序。 •固体排放阀,插头或球型,气动操作。

•CIP和/或可用的蒸汽灭菌 •蒸汽过滤器,配有自动过滤器后清洗系统。 •进样阀 •可选的菜刀 •计算机控制手册,或与PLC,PC和DCS •电子预接线的机 •设计和制造,如ASME,TUV等国际组织的要求 •无害环境和安全操作

PHARMADRY® Vacuum horizontal paddle dryer

The PHARMADRY® horizontal vacuum paddle dryer was primarily developed for  the drying of pharmaceutical ingredients and fine chemicals. Besides its low capital investment costs major advantages of this dryer are its short cycle times, the prevention of contamination by foreign matter, its simple operation and easy validation as well as facilitated cleaning and inspection. The dryer is particularly suited to be used in clean rooms and for sterile applications. The machines are designed and built per cGMP and FDA guidelines.

The important features of the PHARMADRY® are: •  Cylindrical, horizontal vessel with flat welded back cover and a hinged flat front door opening up over the entire vessel diameter. With the door open, the internals of the machine are fully accessible for cleaning and inspection purposes. •  All surfaces in contact with the product such as the vessel, back cover, front door, agitator and vapour filter are heated, providing very efficient heat exchange. •  The cylindrical vessel, the back cover, the front door and the agitator are machined to assure the smallest possible tolerances between agitator and vessel walls. •  Smallest possible tolerances also permit good heat exchange and prevent product adherence. •  All internal surfaces are mirror polished, to improve the flow behaviour of powdery products, the prevention of microdeposits as well as to facilitate cleaning. •  The agitator is installed at the back of the dryer, supported on one side of the vessel only -  The agitator is designed to meet the requirements of this particular dryer type to assure good and even mixing action throughout the dryer volume, also in reverse operation, to provide good discharging characteristics and at the same time reduce friction on the product to a minimum to prevent local overheating as well as to prevent directional thrust or local product compression. -  Speed adjustable using frequency converters with electric drives or control valves with hydraulic drives -  Sealing of the agitator shaft with double mechanical seal or stuffing box.

•  Mechanical seal: the mechanical seal is installed on the rear cover, and is well accessible for cleaning and maintenance purposes. Dry or wet running mechanical seals may be installed.

•  Advantages of the mechanical seal: -  Better final vacuum -  No hazardous leakage or emissions -  No product contamination -  Possibility of sterile operation -  Failure detection system for mechanical    seal

•  Stuffing box with multiple lip seals for undemanding applications. •  Solids discharge valve, plug or ball type, pneumatically operated.

•  CIP and / or steam sterilization available •  Vapour filter, equipped with automatic filter back-cleaning system. •  Sample valve •  Optional choppers •  Machine controls manual, or with PLC, PC and DCS •  Electric pre-wiring of machine •  Design and manufacturing to the requirements of international organizations such as ASME, TÜV, etc. •  Environmentally sound and safe to operate


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